Introduction

GoForth evolves an initial population of molecules (SMILES) using reaction transforms (SMIRKS) to create a virtual library (more SMILES).

Motivation:

Virtual libraries have (V)HTS utility.
Virtual is cheaper than actual.
Illustrate power of Reaction Toolkit and reaction transforms.
Biogenesis research (Harold Morowitz, Geo. Mason University).

GoForth is a contrib program written with DayPerl.

Daylight software used:

Reaction Toolkit
Thor DB system

EuroMUG'99 -- 28-29 October 1999 -- Cambridge, UK

Daylight Chemical Information Systems Inc.
info@daylight.com