Scientists in pharmaceutical companies are flooded with data from a plethora of sources. It has become a significant challenge to organize this information in a format which is clear and easily accessible. We are addressing this problem by developing a web-based software environment which integrates a variety of commercial, academic, and home grown tools. The system can be use to perform a variety of functions including database searching, reagent selection, and combinatorial library design. This presentation will focus on benefits as well as the caveats associated with building such a system.