LeadFinder™ Testing & Results
MAO dataset, Abbot Labs, Dr. Yvonne Martin
- Structural Families:
- Found families regardless of representatives in dataset
- Found families regardless of potency of compounds
- Found outliers not consistent with discovered SARs
- Obtained useful SARs to guide lead optimization
- Potential Pharmacophore Families
- Identified pharmacophore points in structural families
- Coalesced structural families into hypothesized pharmacophore families