Generic Reactions:

How do they work?

What if we express the substrate as a pattern, rather than a single molecule?

This represents the set of reactions where the pattern matches the substrate molecule, and the set of atom/bond changes occurs.

SMIRKS:

[c,$(C=C):1][CH2:2][Br:3].[O-:4][C:5](=[O:6])[CH3:7]>> [c,$(C=C):1][CH2:2][O:4][C:5](=[O:6])[CH3:7].[Br-:3]

or, in 4.61,

[c,$(C=C):1][CH2:2]Br>>[c,$(C=C):1][CH2:2]OC(=O)C