A program for generation of chemical structure based on Daylight's SMILES Toolkit has been created. SMARTS patterns and several metrics have been used to constrain production, and resulted in FINGERPRINT similarities to WDI03.4 over 0.8 indicating moderate `drug-likeness.'' The branching metric reflects straight and branched sidechains and the cyclization metric appears to parallel the number of rings. The smaller structures have more rings and the larger structures more branching. This phenomenon will be investigated further. The complexity metric consistently scored the most dissimilar ``drug-like'' structures with higher values. Work with the complexity metric is preliminary and will be investigated further. A systematic method has been created to record the history of assembly and position the starting point of construction. Future work in this area will include effort towards evaluating ``ease of synthesis.''
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