Bridged Cluster Anomaly

Bridged ‘cluster carbons’ create a cage-like carbon structure. It is tempting to predict that the lower surface-to-volume ratio in the ‘caged’ structure would require an even greater negative correction, while the data show that it is positive.

Meas. logp Ps 18 analogs from K. Lodge, J.Chem.Eng. Data 1999, 44, 1321-1324. Improves ClogP for aldrin, dieldrin, mirex etc.

Bridged ‘cluster carbons’ create a cage-like carbon structure. It is tempting to predict that the lower surface-to-volume ratio in the ‘caged’ structure would require an even greater negative correction, while the data show that it is positive.