Revised Hydrophobic Parameter
Log P (A/O) = 0.95 V - 0.34 ?* - 3.2 ?? - 2.0 ?? - 0.22
?(A/O) reflects the subsituent contribution to measure of mixed polarity & vol.
?(A/O) -OMe on benzene = -0.03 (i.e., volume & polarity cancel)
?(A/O) p-OMe for above = -0.07 ?(A/O) m-OMe for above = -0.22 ?(A/O) o-OMe for above = -0.21
??(A/O) 3,4-(OMe)2 above = - 0.68 (Oct ???= -0.11) ??(A/O) 2,3-(OMe)2 above = + 0.64 (Oct ?? =+0.08) ??(A/O) 2,3-(OMe)2 benzene = - 0.83 (Oct ?? = -0.53)