Diversity Hypothesis Not Supported

• Amide library
  • selecting 40x40 from 400x400
  

Random 0.510 (0.004)

Reactant Based 0.594

Product Based: Library 0.651

Product Based: Combinatorial Library 0.623

• Product based selection is more effective than reactant based selection

• Product based selection does not necessarily result in a combinatorial library

• Combinatorial libraries can also be selected at the product level with increased diversity
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