Fusion Of Similarity Coefficients
Similarity searches of 20 target structures with anti-AIDS activity against the full NCI AIDS database
Searches carried out using each of the 12 coefficients, and the resulting rankings fused to give rankings corresponding to all combinations of 1, 2, 3…10, 11, 12 coefficients
The effectiveness of a combination was evaluated by the number of actives in the top-400 positions of the fused ranking